LETROMINA ( LETROZOLE) 2.5MG

Antitumor agent. It is a non-steroidal inhibitor of aromatase, an enzyme with the participation of which estrogen is synthesized in postmenopausal women. Aromatase promotes the conversion of androgens synthesized in the adrenal glands (primarily androstenedione and testosterone) into estrone and estradiol. Inhibition of aromatase activity is realized through competitive binding to the subunit of this enzyme - the cytochrome P450 heme, which leads to a decrease in estrogen biosynthesis in all tissues, including. in tissues of estrogen-dependent tumors.